CoaLAB 1000

CoaLAB 1000, Compact bench top fully automated clotting, chromogenic and immunoturbidimetric coagulation analyser for precise and reliable results over the entire coagulation spectrum

MEASURING PRINCIPLE

The analyser uses a photo-optical detection principle. Clotting, chromogenic and immunologic assays can be run simultaneously in random access, depending on the available wavelength installed in the analyser.

The measuring module consists of the measuring rotor having two measuring channels each equipped with LED photometer. Depending on the analyser there are either

– 2 LED photometers with a filter 405nm only or

– 2 LED photometers with filters at 405nm/570nm/740nm

A light beam passes through the cuvette and is received by the photodiode. As soon as the starting reagent is added to the plasma, the measuring time starts.

Any change in the light transmittance is detected and converted into an electrical signal by the photodiode. When the assay is complete, the raw data (seconds for coagulation assays and mE/sec (Extinction) for chromogenic assays) are processed and reported.

Totally automated two channel coagulation analyser for clotting, chromogenic and immunological assays.

Capable of performing routine clotting assays like PT, APTT, fibrinogen, thrombin time, ecarin time, batroxobin, factor assays and latex assays like D-Dimer, CRP and chromogenic assays like AT3, protein C, plasminogen, α 2 antiplasmin, as well as tests like Factor V Leiden, LA, PiCT, TDT, and TAFI etc.

- The system offers comprehensive testing capabilities covering most coagulation tests including routine, special and emerging tests, addressing future needs as well.

Touch sensitive LCD display with on board graphic user interface, and no need for external computer.

- Provides easy guidance for operator and intuitive software for easy operation and usage and minimum space requirement.

The system is based on the photometry with magnetic stir bars to homogenise the approach and to increase the sensitivity.

- Based on the well proven and unique principle combining the best of photometry and continuous mechanical stirring, for precise results even in the case of tests involving fragile clots.

Two channel LED photometer with two reference channels.

- Relatively impressive throughput of 120 PTs, 60 APTTs and 80 fibrinogen tests per hour, in a compact foot print and precise results, thanks to referencing.

Has 32 cuvette ring rotor, 22 sample positions for the primary and or secondary tubes, and 15 regent positions and three stat positions.

- Provides for carrying out a number of tests without the need for exchange, or intervention with total automation, adequate and practical in most laboratory conditions.

The test volume is 150μl typically and 300μls maximum, providing for easy

adaptation to different tests and methodologies.

- Offers economy of scale for the expensive tests, with flexibility for easy adaptation of specific and appropriate reagents, to suit the lab requirement.

Provides for automation with result calculation in percentage, INR, ratio, mg/dl, g/l, μg/ml etc. automatic predilution of the samples, automatic repeat function, automatic calibration and so on.

- Total automation, in every practical aspect providing greater level of convenience and accuracy.

Memory of 10,000 results and curve data on internal SD-card.

- Helps in tracking the activity curve, and helps in easy diagnosis of certain abnormalities, providing the function what is known as “wave-form analysis” and first adapted by LABiTec!

Large data storage capacity without PC and associated hardware.

Patient ID can be entered manually, or, with the optional barcode scanner, in addition to on-board barcode scanning facility.

- Fail proof back-up for sample i.d. with entry of patient identification to avoid sample mix up even in the unlikely event of barcode scanner failure.

Internal USB interface for easy adaptation of other assays and field software updates.

- Ensures easy system upgradation in the field and protects against obsolescence.

Offers positive barcode identification and with the bi-directional host query/LIS communication as standard.

- Hassel free data transfer with host query for great convenience and data handling.

The CoaLab 1000 automated open system to reagents, quite compact in its design and big in performance, occupies very little bench space, offering great ease of use while incorporating all the features normally seen with larger and much more expensive analysers, with the ideal throughput which in most situations is adequate for medium and high end facilities without huge initial investment, but a system that meets your needs today and well into the future under Indian conditions.

CoaLAB 1000

The CoaLAB 1000 named hereafter as analyser, is a fully automated photo-optical

blood plasma hemostasis instrument capable of performing clotting, chromogenic* and immunoassays* simultaneously in random access or batch mode from primary and secondary tubes.

For in-vitro diagnostic use only!

* Depending on the analyser model the system is capable to perform a wide range of coagulometric, chromogenic and immunologic coagulation tests such as Prothrombin time, activated and partial Thromboplastin time, Fibrinogen, derived Fibrinogen and special tests such as single factor assays, Anti-Thrombin III, Protein C, Protein S, C-Reactive Protein, D-Dimer and others based on the wavelength available in different analyser types.

Automated Coagulation Analyser

Totally automated bench top coagulation analyser which (i) shall be a stand alone device, without calling for external PC and monitor to control and run software and save space. (ii) Can permit flexible add-on field upgradable software to protect against obsolescence. (iii) Can offer various wavelengths to cover all major coagulation tests existing and emerging.

1. Instrument type – Fully automated coagulation analyser for the clotting, chromogenic and immunologic testing with cover for safety.
2. Display – Touch sensitive colour display with on-board graphic user interface.
3. 1. Measuring principle – Photometric LED photometer (405nm, 570nm, 740nm) with two reference channels.
   2. No. of measuring channels – Two, simultaneously.
4. Measuring unit – Controlled at 37ºC ± 0.4 ºC. or better in a ring rotor, housing a minimum of 32 cuvettes.
5. Sample/reagent platform – At least 2×11 Sample positions for various primary and secondary tubes, between 1.7 and 4 ml.
   3 – 5 Stat positions.
   Minimum 15 x Reagent positions (3x15ml) stirred, (12x5ml) non-stirred. Removable reagent tray for overnight cooling/ storage.
   8 -10 Positions for controls and dilutions.
   2 x Wash/cleaner positions with variable wash cycles.
6. Sampling – Dilutor, 2 to 250µl, volume freely programmable with capacitive sensor for pipetting, that can move in three directions. Pipettor ideally heated to 37ºC to preheat sample/reagent before testing
7. Test volume – 150 µl typically and not exceeding 300 µl
8. Maximum tests during same run – Ten tests per run depending on reagents/ buffers used.
9. Assays to be covered – The following and not limited to routine clotting: PT, APTT, Fibrinogen, Thrombin time, Ecarin, Batroxobin etc.
   Factors: Extrinsic (II, V, VII ), Intrinsic (VIII, IX,XI, and XII ) etc.
   Thrombosis risk: Protein C, Protein S, Lupus anticoagulant, Factor V Leiden, APC-resistance, PiCT, TDT, TAFI and so on. Chromogenic: Protein C, Protein S, Anti-Thrombin III, Plasminogen, α2-Antiplasmin etc. Immunoturbidimetric : D-Dimer, CRP etc.
10. Data management – On-board QC package with Levy-Jennings plot, and Westguard multi rules.
11. Software/hardware features – 50 or more programmable memory for reagents and test locations individually editable. Optimised cuvette consumption capability.
12. 1. Additional functions – Interface 2x RS232 barcode scanner
    2. 2xUSB device (printer)
    3. LAN (Host ) for bidirectional host communication.
    4. SD card, chip card loading unit.
13. Power supply – 220V and 50 Hz. + 10%

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